鎽樿锛氭枃绔犲垎鏋愪簡鐏浕寤犲虎姘寸殑鐗归粸(di菐n)锛屾彁鍑轰簡鐏浕寤犲虎姘存柊鐨勫垎椤炴柟娉�(濡傚皣寤㈡按鍒嗘垚鐒�(w煤)闇€鑴菇铏曠悊銆侀渶瑕佽劔楣借檿鐞�銆佸彲寰挵(hu谩n)浣跨敤鍜屼笉鑳藉洖鐢ㄧ瓑4椤�)锛涘垎鏋愪簡鐏浕寤犲悇椤炲虎姘寸殑鍥炵敤鐝�(xi脿n)鐙€锛涜◣璜栦簡寤㈡按鐨勫洖鐢ㄦ柟寮�(濡備綆鍚菇閲�銆侀珮鍚菇閲忓虎姘寸殑鍥炵敤鍜屽叾浠栧虎姘寸殑鍥炵敤)锛涙寚鍑轰簡寤㈡按缍滃悎鍒╃敤鐨勬妧琛�(sh霉)瑕侀粸(di菐n)锛岀壒鍒ュ挤(qi谩ng)瑾�(di脿o)浜嗗虎姘寸稖鍚堝埄鐢ㄧ殑闂�(gu膩n)閸垫槸鍦ㄦ彁楂樼伆姘存瘮鍜屽惊鐠�(hu谩n)姘存績绺€嶇巼鐨勫熀绀�(ch菙)涓婁娇楂樺惈楣介噺鐨勫虎姘撮噺鑸囨矕鐏扮郴绲�(t菕ng)鐨勮(b菙)姘撮噺鐩稿尮閰�銆�

    鐏浕寤犵殑绡€(ji茅)姘撮€斿緫鍖呮嫭閲囩敤绌哄喎鎶€琛�(sh霉)銆佹彁楂樺惊鐠�(hu谩n)姘存績绺€嶇巼銆侀枊(k膩i)灞曞虎姘村洖鐢ㄧ瓑銆傚叾涓�锛岀┖鍐峰叿鏈夎€楁按閲忓皯鐨勫劒(y艒u)榛�(di菐n)锛屼絾鐔辨晥鐜囦綆锛屽彧鑳界敤浜庡寳鏂瑰毚(y谩n)閲嶇己姘寸殑鍦板崁(q奴)銆傚虎姘村洖鐢ㄦ槸鐏浕寤犵瘈(ji茅)姘存笡鎺掔殑閲嶈閫斿緫锛岄€氶亷(gu貌)寤㈡按鍥炵敤锛屽彲浠ユ浛浠ｇ伀闆诲粻30锛� 浠ヤ笂鐨勬柊楫按锛岀瘈(ji茅)姘存經鍔涘法澶�锛涘悓鏅�(sh铆)鍙堝彲浠ユ笡灏戦浕寤犵殑寤㈡按澶栨帓閲�锛屾笡杓曞皪(du矛)鐠�(hu谩n)澧冪殑姹℃煋銆傚洜姝�锛屽皪(du矛)寤㈡按缍滃悎鍒╃敤锛屽(sh铆)鐝�(xi脿n)寤㈡按璩囨簮鍖�锛屽凡鎴愮偤鐏浕寤犲(sh铆)鐝�(xi脿n)鍙寔绾�(x霉)鐧�(f膩)灞曠殑蹇呯敱涔嬭矾銆�

    1 鐏浕寤犲虎姘寸殑鐗归粸(di菐n)鍜屽垎椤�

    1锛�1 寤㈡按鐨勭壒榛�(di菐n)

    鑸囧寲宸�銆侀€犵礄绛夊伐妤�(y猫)寤㈡按鐩告瘮锛岀伀闆诲粻鐨勫虎姘存湁浠ヤ笅鐗归粸(di菐n)锛�

    (1)寤㈡按鐨勭ó椤炲緢澶氾紝姘磋唱(zh矛)姘撮噺宸暟寰堝ぇ銆傞浕寤犱富瑕佺殑寤㈡按鍖呮嫭寰挵(hu谩n)姘存帓姹℃按銆佺伆娓ｅ虎姘�銆佸伐妤�(y猫)鍐峰嵒姘存帓姘�銆佹(j墨)绲勯洔鎺掓按銆佸惈鐓ゅ虎姘淬€佹补搴�(k霉)娌栨礂姘�銆佸寲瀛�(xu茅)姘磋檿鐞嗗伐钘濆虎姘淬€佺敓娲绘薄姘寸瓑銆�

    (2)寤㈡按涓殑姹℃煋鎴愬垎浠ョ劇(w煤)姗�(j墨)鐗╃偤涓汇€傚湪鐢熺敘(ch菐n)閬�(gu貌)绋嬩腑閫�(j矛n)鍏ユ按楂旂殑鏈夋(j墨)姹℃煋鐗╀富瑕佹槸娌�锛屽叾浠栨湁姗�(j墨)鎴愬垎寰堝皯銆�

    (3)闁撴柗鎬ф帓姘磋純澶�銆�

琛�1鐐虹伀闆诲粻骞剧ó涓昏寤㈡按鐨勭壒榛�(di菐n)鍒嗘瀽銆�

琛�1 鐏浕寤犲虎姘寸殑鐗归粸(di菐n)鍒嗘瀽 
 

    1锛�2 寤㈡按鐨勫垎椤�

    灏�(du矛)寤㈡按閫�(j矛n)琛屽悎鐞嗙殑鍒嗛鏄虎姘寸稖鍚堝埄鐢ㄧ殑鍩虹(ch菙)锛屽悓涓€椤炲虎姘村彲浠ラ噰鐢ㄥ悓涓€椤炶檿鐞嗗伐钘濆(sh铆)鐝�(xi脿n)鍥炵敤銆傜洰鍓�锛岀伀闆诲粻寤㈡按鐨勫垎椤炰富瑕佹槸鎸夌収寤㈡按鐨勪締(l谩i)婧愮⒑瀹氱殑锛岀ó椤炲緢澶�锛岃垏鍥炵敤娌�(m茅i)鏈夌洿鎺ョ殑闂�(gu膩n)绯�銆傛牴鎿�(j霉)鐏浕寤犲悇椤炲虎姘寸殑姘磋唱(zh矛)姘撮噺鐗归粸(di菐n)锛屼互铏曠悊鍥炵敤鐐虹洰妯�(bi膩o)锛屽彲浠ュ皣鐏浕寤犵殑寤㈡按鍒嗙偤浠ヤ笅骞鹃锛�

    (1)涓嶉渶瑕佽劔楣借檿鐞嗗嵆鍙洖鐢ㄧ殑浣庡惈楣介噺寤㈡按銆傞€欓寤㈡按鍖呮嫭姗�(j墨)绲勯洔鎺掓按銆佸伐妤�(y猫)鍐峰嵒姘寸郴绲�(t菕ng)鎺掓按銆佺敓娲绘薄姘寸瓑銆傞€欓儴鍒嗘按鐨勫叡鍚岀壒榛�(di菐n)鏄湪浣跨敤閬�(gu貌)绋嬩腑鍚菇琛�1 鐏浕寤犲虎姘寸殑鐗归粸(di菐n)鍒嗘瀽閲忔矑(m茅i)鏈夋槑椤殑鍗囬珮锛屽洖鐢ㄨ檿鐞嗙郴绲�(t菕ng)涓嶈€冩叜鑴菇锛岃檿鐞嗗悗鐨勬按璩�(zh矛)鍙互閬�(d谩)鍒版垨鎺ヨ繎宸ユキ(y猫)姘寸殑姘磋唱(zh矛)妯�(bi膩o)婧�(zh菙n)锛岀敋鑷冲彲浠ユ浛浠ｆ柊楫按婧愩€傞€欓姘寸殑娣卞害铏曠悊鎴愭湰鐩稿皪(du矛)杓冧綆锛屽洜姝ょ洰鍓嶅湪闆诲粻涓洖鐢ㄧ殑姣斾緥杓冮珮銆�

    (2)闇€瑕佽劔楣借檿鐞嗘墠鑳藉洖鐢ㄧ殑楂樺惈楣介噺寤㈡按銆傞€欓寤㈡按鐨勭壒榛�(di菐n)鏄按鍦ㄤ娇鐢ㄩ亷(gu貌)绋嬩腑鍥�?y脿n)闂堥オs鎴栬€呭姞鍏ヤ簡閰�銆佸牽銆侀菇鑰屼娇鍚菇閲忓ぇ骞呭害鍗囬珮锛屼竴鑸惈楣介噺鍙仈(d谩)宸ユキ(y猫)姘寸殑鏁�(sh霉)鍊嶄互涓�銆傚吀鍨嬬殑渚嬪瓙鏈夊弽婊查€忔績鎺掓按銆侀洟瀛愪氦鎻涜ō(sh猫)鍌欏啀鐢熷虎姘�銆佸惊鐠�(hu谩n)姘存帓姹℃按绛夈€傞€欑ó姘撮櫎浜嗙敤浜庢矕鐏�銆侀櫎娓�銆佺叅鍫�(ch菐ng)鍣存穻涔嬪锛屽洖鐢ㄥ繀闋堢稉(j墨ng)閬�(gu貌)鑴菇铏曠悊锛屽洜姝ゅ洖鐢ㄧ郴绲�(t菕ng)姣旇純寰�(f霉)闆�锛屽洖鐢ㄦ垚鏈瘮杓冮珮锛屾墍浠ョ洰鍓嶇殑鍥炴敹鍒╃敤鐜囪純浣�銆傚洜?y脿n)姒�?j墨ng)婵�(j矛)鐨勫師鍥狅紝寰挵(hu谩n)姘存帓姹℃按鐨勫洖鏀惰檿鐞嗗繀闋堝湪杓冮珮鐨勬績绺€嶇巼涓嬫墠鑳藉(sh铆)鐝�(xi脿n)銆傚悇闆诲粻寰挵(hu谩n)姘存帓姹℃按鐨勫惈楣介噺鍥犺(b菙)鍏呮按姘磋唱(zh矛)鍜屾績绺€嶇巼鐨勪笉鍚岃€屽樊鍒ュ緢澶с€傚瀵堕洖绗簩鐧�(f膩)闆诲粻锛屾績绺€嶇巼閬�(d谩)鍒�5宸﹀彸锛屽惊鐠�(hu谩n)姘存帓姹℃按鐨勫惈楣介噺?j墨)H鐐� 1 200 mg锛廘锛涜€屽北瑗挎煇浜涢浕寤�锛屾績绺€嶇巼鐐�2锛岃€屽惈楣介噺灏遍仈(d谩)鍒�1 000 mg锛廘浠ヤ笂銆�

    (3)寰挵(hu谩n)浣跨敤鐨勫虎姘�銆傞€欓寤㈡按鍖呮嫭鍚叅寤㈡按銆佹矕鐏伴櫎娓ｅ虎姘�銆傞€欓儴鍒嗗虎姘寸殑姘磋唱(zh矛)姣旇純鐗规畩锛岄€氬父鎳告诞鐗╁緢楂�銆傚惈鐓ゅ虎姘寸殑鎳告诞鎴愬垎涓昏鏄叅绮�锛岀伆姘村墖涓昏鏄伆绮�銆傚彟澶�锛岀伆娓ｅ虎姘寸殑鍚菇閲忓拰pH閮芥瘮杓冮珮(浠ュ墠鐨勬按鑶滈櫎濉电郴绲�(t菕ng)鐏版按鐨刾H杓冧綆锛岀従(xi脿n)鍦ㄥ凡姣旇純灏�)銆傜敱浜庣祫鍒嗘瘮杓冪壒娈�锛屽洜姝ら€氬父涓嶈垏鍏朵粬寤㈡按娣峰悎铏曠悊锛岃€屾槸鍠崹(d煤)铏曠悊鍚庡惊鐠�(hu谩n)浣跨敤锛涜檿鐞嗗伐钘濅互娌夋穩鐐轰富锛岀洰鐨勬槸闄ゅ幓姘翠腑鐨勬嚫娴墿銆�

    (4)涓嶈兘鍥炵敤鐨勬サ宸殑寤㈡按銆傞€欎簺寤㈡按姘磋唱(zh矛)妤靛樊锛屽洜铏曠悊鎴愭湰妤甸珮鑰屾矑(m茅i)鏈夊洖鐢ㄥ児(ji脿)鍊�銆備緥濡傝劔纭虎姘�锛屽叾鍚菇閲�銆佹嚫娴墿銆侀噸閲戝爆闆㈠瓙鍚噺閮藉緢楂�锛屼絾姘撮噺杓冨皬锛屼竴鑸柈鐛�(d煤)铏曠悊鍚庨仈(d谩)妯�(bi膩o)鎺掓斁銆傞倓鏈変竴浜涢潪缍�(j墨ng)甯告€у虎姘�锛屽鍖栧(xu茅)娓呮礂寤㈡按銆佺┖闋�(y霉)鍣ㄧ厵姘ｅ伌(c猫)娌栨礂寤㈡按绛夐兘鍙兘鎺掓斁銆�

    2 寤㈡按鐨勬敹闆嗗晱(w猫n)椤�

    (1)鍥�?y脿n)妤﹂珛娼橆嚀c(di菐n)鐨勫垎甯冩瘮杓冨京(f霉)闆�锛屼笉鍙兘灏囨瘡绋虎姘村柈鐛�(d煤)鏀堕泦锛屼絾鍙互鐩￠噺鍦版寜鐓у虎姘磋檿鐞嗗伐钘濈殑鐣板悓渚�(l谩i)鏀堕泦銆�

    (2)闆诲粻鐨勫虎姘翠竴鑸槸鐒�(w煤)澹撴按锛屽叾鏀堕泦涓昏閫氶亷(gu貌)婧濋亾瀹屾垚銆傚虎姘存敹闆嗘簼閬撶殑娉勬紡鏄櫘閬嶅瓨鍦ㄧ殑鍟�(w猫n)椤�銆傚湪鍗楁柟鍦板崁(q奴)锛屽洜?y脿n)姒堝彽婊ゎ啣妗�?锛屽湴鍩鸿粺锛屾簼閬撳鏄撳洜涓嶅潎鍕绘矇闄嶈€岀櫦(f膩)鐢熼枊(k膩i)瑁�锛屽皫(d菐o)鑷村虎姘村婧㈡垨鍏�(n猫i)婊�銆傚婧㈠皪(du矛)鍦颁笅姘寸殑姘磋唱(zh矛)鏈夋薄鏌�锛岃€屼笖寤㈡按鍦ㄦ敹闆嗛亷(gu貌)绋嬩腑鎼嶈€楅亷(gu貌)澶�锛屼笉鍒╀簬姘撮噺鐨勫钩琛★紱鍏�(n猫i)婊叉按鍓囨渻(hu矛)褰遍熆寤㈡按鐨勬按璩�(zh矛)銆傚鏋滃湴涓嬫按鍚菇閲忔瘮寤㈡按鐨勯珮锛屽墖鏈夊彲鑳藉奖闊垮虎姘寸殑鍥炵敤銆傚鍦ㄦ湁浜涙勘娴烽浕寤�锛屾泛灞ゅ湴涓嬫按鐨勫惈楣介噺寰堥珮锛屽嵆浣垮皯閲忔徊鍏ヤ篃鏈�(hu矛)浣垮虎姘寸殑鍚菇閲忓緢楂�锛屽奖闊垮叾浣跨敤銆傚湴涓嬫按鐨勬按浣嶉倓鍙楁捣娼疆浣嶇殑褰遍熆锛氭疾娼檪(sh铆)锛屽湴涓嬫按浣嶅崌楂�锛屽収(n猫i)婊插毚(y谩n)閲嶏紱钀芥疆鏅�(sh铆)锛屽湴涓嬫按浣嶉檷浣�锛屽虎姘村婧�銆�

    (3)鍦ㄧ敤娴锋按鍐峰嵒鍑濇苯鍣ㄧ殑闆诲粻锛屾捣姘存渻(hu矛)鍥犻殧闆笉瀹屽杽鑰屾贩鍏ュ虎姘存敹闆嗙郴绲�(t菕ng)銆傚洜娴锋按鐨勫惈楣介噺妤甸珮锛屽線寰€灏戦噺鐨勬硠婕忎篃鏈�(hu矛)浣垮虎姘寸殑姘磋唱(zh矛)鍔ｅ寲锛屼娇鏀堕泦鐨勫虎姘村け鍘讳娇鐢ㄥ児(ji脿)鍊�銆傚父瑕�(ji脿n)鐨勬硠婕忕櫦(f膩)鐢熷湪涓诲粻鎴垮虎姘存敹闆嗙郴绲�(t菕ng)銆�

    (4)鏌愪簺娆插洖鏀剁殑闁撴柗鎬у虎姘寸殑鏀堕泦绯荤当(t菕ng)鏈夋檪(sh铆)闇€瑕佹敼閫犮€傚寰挵(hu谩n)姘存帓姹℃按鐨勭灛鏅�(sh铆)姘存祦閲忓緢澶�锛屽鏋滆檿鐞嗗洖鐢�锛屽墖蹇呴爤灏囧叾鏀圭偤閫ｇ簩(x霉)鎺掓薄锛屽緸寰挵(hu谩n)姘存车鍑烘按绠￠亾寮曞嚭閫ｇ簩(x霉)姘存祦閫�(j矛n)琛岃檿鐞嗐€�